Secrier Lab
Computational Cancer Genomics and Immunology @ UCL Genetics Institute
The Secrier lab at the UCL Genetics Institute works at the interface of genomics and immunology. Our main research focus is cancer, and in this arena we are interested in understanding the evolution of genomic instability during cancer development and progression, and how this links to changes in the tumour microenvironment and impacts immune responses. We aim to address this by developing new computational methods for the identification of large-scale events contributing to genomic instability, probabilistic models that link genetic changes and immune activity, and methods for inferring the timing and genetic features of key points in cancer progression. We have also recently started to explore genetic factors linked to risk and progression in neurodegenerative diseases.
Posted 30 Jul 2018
Posted 19 Jun 2018
Posted 01 Oct 2016